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Lovaxin C Lovaxin C is a live attenuated ''Listeria'' cancer vaccine that is under investigation (2008) and has entered clinical trials. It is under development at Advaxis. Note: Lovaxin C has been renamed ADXS11-001 ==Background== The bacterial genus ''Listeria'' includes intracellular pathogenes able to induce a strong activation of the immune system. The vaccine is derived from bioengineered ''Listeria monocytogenes'' that have been attenuated and produce a tumor antigen. Lovaxin C specifically contains HPV-16-E7 antigen specific for cervical carcinoma. Women with cervical cancer are thought to be able to mount a more effective immune response against this cancer after stimulation with the vaccine. The concept has been tested in a mouse model where the vaccine led to regression of renal and colon cancer.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Lovaxin C」の詳細全文を読む
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